home
***
CD-ROM
|
disk
|
FTP
|
other
***
search
/
Shareware Overload Trio 2
/
Shareware Overload Trio Volume 2 (Chestnut CD-ROM).ISO
/
dir26
/
med9410o.zip
/
M94A2726.TXT
< prev
next >
Wrap
Text File
|
1994-10-25
|
2KB
|
39 lines
Document 2726
DOCN M94A2726
TI Detection of HIV-2 antibodies in saliva.
DT 9412
AU Fang C; Hofman L; Lugalia L; Saliva Diagnostic Systems, Inc. (SDS),
Vancouver, WA 98682.
SO Int Conf AIDS. 1994 Aug 7-12;10(1):239 (abstract no. PB0385). Unique
Identifier : AIDSLINE ICA10/94369849
AB Although the presence of HIV-1 antibodies in saliva of infected patients
has been widely documented, few publications refer to HIV-2 antibodies.
Results on saliva from 18 HIV-2 infected individuals are described here.
Saliva and serum specimens were collected from five known HIV-2 infected
patients in the United States but of West African origin. Saliva was
collected using the Omni-SAL collection device (Saliva Diagnostic
Systems, Inc., Vancouver, WA). Abbott HIVAB HIV-1 EIA, BioChem
ImmunoSystems Detect HIV-1/-2 EIA, Genetic Systems HIV-1/HIV-2 EIA and
HIV-2 EIA, and Waldheim Pharmazeutika Fluorognost HIV-1 IFA and HIV-2
IFA were performed on all serum and saliva specimens. In addition,
Orgenics ImmunoComb BiSpot HIV-1 and HIV-2 was performed on saliva
specimens. Testing procedures had been optimized for saliva. All saliva
and serum specimens were positive by HIV-2 and HIV-1/2 assays. Cross
reactivity with HIV-1 was observed in all sera but only in 40% of saliva
specimens. Serum and saliva paired specimens were collected from an
additional 13 HIV-2 infected individuals in the Ivory Coast. All serum
specimens were shown to be positive for HIV-2 antibodies with Cambridge
Biotech HIV-2 Western blot assay. Saliva specimens were tested with the
Genetic Systems HIV-2 EIA, using an optimized in-house protocol. Sera
were tested using the manufacturers protocol. All were positive. In
summary, saliva from all HIV-2 infected individuals contained HIV-2
antibodies as measured by EIA and IFA.
DE Comparative Study Cote d'Ivoire Cross Reactions Human HIV
Antibodies/*ANALYSIS HIV Seropositivity/*DIAGNOSIS/IMMUNOLOGY
HIV-1/IMMUNOLOGY HIV-2/*IMMUNOLOGY Immunoenzyme Techniques Predictive
Value of Tests Saliva/*IMMUNOLOGY United States MEETING ABSTRACT
SOURCE: National Library of Medicine. NOTICE: This material may be
protected by Copyright Law (Title 17, U.S.Code).